Testosterone Therapy for Women in San Francisco: The Missing Hormone in Midlife Health

Many active, high-achieving women in their 40s, 50s, and 60s begin noticing subtle but significant changes in energy, strength, focus, and libido. They are eating well, exercising consistently, building successful careers, and prioritizing wellness — yet something feels different.


In many cases, one critical hormone is missing from the conversation: testosterone.


At Rejuv Medical in San Francisco’s Mission Bay, we work with women across the Bay Area who are proactive about longevity and performance. For many of them, optimizing testosterone levels becomes a pivotal step in restoring vitality and confidence.


The Importance of Testosterone in Women

Testosterone is often misunderstood as a “male hormone,” but it plays an essential role in female physiology. Women naturally produce testosterone in the ovaries and adrenal glands. It contributes to:

  • Lean muscle mass and strength
  • Metabolic function and body composition
  • Cognitive clarity and focus
  • Libido and sexual responsiveness
  • Mood stability and motivation
  • Bone density

Testosterone levels begin declining in a woman’s 30s and continue to decrease through perimenopause and menopause. By midlife, many women have experienced a significant drop compared to peak levels in early adulthood.


Despite its importance, testosterone is frequently under-evaluated and under-prescribed in women’s healthcare.

Why Testosterone Therapy Is Often Overlooked

There are several reasons testosterone therapy remains underutilized:

  • Persistent misconceptions that testosterone is inappropriate for women
  • Limited provider training in bioidentical hormone replacement therapy (BHRT)
  • Overreliance on broad laboratory reference ranges rather than optimal levels
  • Concerns about side effects when dosing is not individualized

When prescribed appropriately and monitored carefully, testosterone therapy can be both safe and transformative.


At Rejuv Medical, we approach hormone therapy through a comprehensive lens — evaluating symptoms, lifestyle, body composition, and advanced lab testing to determine whether testosterone is appropriate.

Testosterone Complements Estrogen and Progesterone Therapy

For many women already on estrogen and progesterone therapy, testosterone provides the missing piece.

Each hormone has a distinct role:



Estrogen supports:

  • Cardiovascular and bone health
  • Vaginal tissue integrity
  • Temperature regulation


Progesterone supports:

  • Sleep quality
  • Anxiety reduction
  • Uterine protection


Testosterone supports:

  • Libido and sexual satisfaction
  • Lean muscle preservation
  • Metabolic resilience
  • Cognitive sharpness
  • Drive and motivation


When balanced correctly, these hormones work synergistically to restore not only symptom relief, but optimal performance and well-being.

Signs of Low Testosterone in Women

Women with low testosterone often describe:

  • Difficulty maintaining muscle despite strength training
  • Increased abdominal fat
  • Reduced libido or sexual responsiveness
  • Brain fog or decreased mental clarity
  • Lower motivation and drive
  • A diminished sense of confidence or vitality


These symptoms are often attributed solely to aging or stress. However, hormonal imbalance may be a significant contributing factor.

Is Testosterone Therapy Safe for Women?

When delivered at physiologic doses and monitored appropriately, testosterone therapy for women can be safe and effective.


At Rejuv Medical in San Francisco, we:

  • Prescribe individualized, low-dose protocols
  • Monitor hormone levels and clinical response
  • Adjust dosing based on symptoms and lab results
  • Combine hormone therapy with nutrition, strength training, and longevity strategies


The goal is not excess — it is optimization.

Testosterone Therapy for Active Women in the Bay Area

The women seeking hormone optimization in San Francisco and the greater Bay Area are often:

  • Entrepreneurs and executives
  • Physicians and healthcare professionals
  • Tech leaders
  • Fitness-focused women
  • Mothers balancing demanding careers


They are not looking to slow down. They are looking to maintain strength, cognitive performance, and metabolic health for decades to come.

Testosterone therapy, when appropriate, can help support that goal.


Hormone Optimization at Rejuv Medical in San Francisco

If you are searching for:

  • Testosterone therapy for women in San Francisco
  • Bioidentical hormone replacement therapy in the Bay Area
  • Hormone optimization near Mission Bay
  • Treatment for low libido in women over 40


Rejuv Medical provides comprehensive hormone evaluations and customized treatment plans tailored to your physiology and lifestyle.


Midlife does not have to mean decline. With the right assessment and individualized care, women can maintain strength, clarity, and vitality well into their 50s, 60s, and beyond.


Schedule a Consultation

If you are an active woman between 40 and 65 in San Francisco or the Bay Area and suspect hormones may be affecting your energy, strength, or confidence, a comprehensive evaluation is the next step.


Testosterone is not just a male hormone. It is an essential component of female health — and when balanced correctly, it can help restore the vitality you expect from your body and mind.

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